Two years into the pandemic, a group of friends throw an online party with a night of games, drinking and drugs. After taking an ecstasy pill, things go terribly wrong and the safety of their home becomes more terrifying than the raging chaos outside.

Chicago 2035, terrorists have attacked. An average man holds the key to a cure. As time runs out and the viral infections reach epidemic proportions, the leaders of government operation attempt to save the man and find the cure.

Six friends test their intelligence in a game that takes a dark turn.