When the notorious Diaper Mafia take hostage the Tromaville School for the Very Special, only the Toxic Avenger and his morbidly obese sidekick Lardass can save Tromaville.

Tromaville has a monstrous new hero. The Toxic Avenger is born when mop boy Melvin Junko falls into a vat of toxic waste. Now evildoers will have a lot to lose.