In foggy London Dr Jekyll experiments on newly deceased women determined to discover an elixir for immortal life. Success enables his spectacular transformation into the beautiful but psychotic Sister Hyde who stalks the dark alleys of Whitechapel for young, innocent, female victims, ensuring continuation of the bloodstained research. With each transformation Sister Hyde becomes the more dominant personality, determined to eventually suppress the frail, ineffectual Dr Jekyll forever.

Based on the story of Elisabeth Bathory, the 18th century Countess who indulged herself in an orgy of murder and vampirism before before being walled up in her room by the authorities. The ageing Countess Dracula discovers that the blood of young virgins has a restorative effect on her celebrated beauty. Years later, she becomes engaged to a handsome young Hussar and is forced to repeat vile atrocities with ever-increasing regularity to hold off old age.