Coffy is a nurse whose younger sister gets involved in drugs and is severely injured by contaminated heroin. Coffy sets out on a mission of vengeance and vigilante justice, killing drug dealers, pimps, and mobsters who cross her path.

The triumphs and failures of middle age as seen through the eyes of runaway American housewife Mary Wilson (Jean Simmons), a woman who believes that ultimate reality exists above and beyond the routine procedures of conscious, uninspired, everyday life. She feels cheated by an older generation that taught her to settle for nothing less than storybook finales, people who are disillusioned and restless and don’t know why, people for whom life holds no easy answers. Great supporting cast includes John Forsythe, Teresa Wright, Lloyd Bridges, Shirley Jones, Bobby Darin, Tina Louise, Dick Shawn, and Nanette Fabray.