In this chilling sequel to 28 Days Later, the inhabitants of the British Isles appear to have lost their battle against the onslaught of disease, as the deadly rage virus has killed every citizen there. Six months later, a group of Americans dare to set foot on the isles, convinced the danger has come and gone. But it soon becomes all too clear that the scourge continues to live, waiting to pounce on its next victims.

Rachel Carson, a best-selling crime novelist, is devastated and filled with guilt over the accidental death of her son. Hoping that a change of scenery will help alleviate her suffering, she leaves her home in the city and moves into a vacant country house owned by a friend and begins a relationship with charming local Angus. But, just as her life is taking a turn for the better, Rachel realizes she’s being romanced by a ghost, leading her to doubt her own sanity.