Vinny and Sebastion, two burnouts, going nowhere in small town suburbia and still riding the high of their high-school days, start a business doing the only thing they have ever excelled at…drugs. With the help of a jealous girlfriend and a rich goth chick, Vinny and Sebastion take on the mob, angry, geeky, frat-boys, and zombies in the search of the perfect high.

After a series of murders occur, two vampire hunters and some FBI agents hunt down the empress vampire who caused the mayhem.