When their father is murdered, three brothers descend upon an Oregon mountain river to spread his ashes. After they arrive, one of their children goes missing. One of the brothers was himself abducted 30 years ago when they visited this same river, but he has blocked the incident out of his mind. Only by unlocking the mysteries inside his subconscious, will they be able find the child.

Although awkward college student Todd Howard is particularly adept at science, he’s paying for school with an athletic scholarship that he will lose should he not fare well in an upcoming boxing tournament. Luckily for Todd, he has inherited the same family curse that once turned his cousin into a werewolf. As he transforms into the hairy, fanged, howling monster, he finds both his physical agility and his popularity skyrocketing — but at what cost?