A teenage interracial couple in the 1950’s rob and steal to escape the bigotry of the American South. But when things turn violent, they are forced to confront the dark secrets of their own.

Dr. Evan Cooper is the ideal match on paper and according to her grandmother, Rose Durham and friends, including an equally pushy wedding planner, for florist Laurel Haverford, who fears to be the last of her generation to get married. Yet she keeps dragging her heels after meeting cocky Stephen Banks, who is all wrong on paper but makes her heart leap by pre chemistry.

Belinda Simpson is now a doctor in a small Missouri town where an unknown plague is spreading fear and resentment amoung the townspeople. One local resident thinks the illness was spread from the town orphanage and wants to see it shut down. Belinda struggles to make sense of the disease and God’s plan for the beleaguered town.

A deadly collision between a train and car lead to an unlikely bond between the train engineer and a young boy who escapes the carnage.