A decade and a half after their seminal indie film launched meteoric filmmaking careers, Splick and Jason find themselves staring at their own individual, pre-midlife crises. Having not spoken to one another since a late-nineties falling out, they’re each grappling with the challenges of stalled careers and relationships, as the hands of time creep ominously past forty-o’clock. Splick’s most recent TV show, centered around his character’s perverse relationship with dessert foods, is unceremoniously cancelled by the network, forcing a return to his childhood bedroom at his mother’s apartment in New York. Frustrated by a barrage of comments about the “good,” “funny,” movies he used to make with his old partner, Jason, Splick determines to seek him out and attempt a reunion.

When word hits the street that a nearby elderly gentleman has a cache of old, rare, and very valuable mint condition comic books, rival comic book shop owners Raymond McGillicuddy (Donal Logue) and Norman Link (Michael Rapaport) both set out to be the first to buy them. But when the old man declines to sell, the former friends turn into enemies, and a friendly rivalry becomes tainted with greed and turns to murder.