Due to a road rage between two buses, an accident occurs which puts the lives of its passengers in jeopardy. But the ones greatly affected by such event are a middle-aged woman named Fiesta (Eugene Domingo), an old and retired family patriarch Tonio (Leo Martinez), and a lad named Caloy (Enchong Dee). These three people are pierced through a single steel bar – a dangerous situation that even their doctors find hard to solve. But even before this unfortunate circumstance, these three have their share of ill-fated lives.

On The Job is about the ambitions and passions of four men trying to make a living, for themselves and their families. It shows the parallels between two prison inmates who are contract killers, and the two agents of the law investigating the murders. As they get caught in a web of machination of corrupt government officials, their jobs lead them on a head-on collision against each other with their loved ones as collateral damage.