On a quest for emotional healing and spiritual awakening, a naturopathic doctor and an accountant join others in the Peruvian Amazon to drink a psychedelic brew called ayahuasca.

U.S Marshal Mike Donovan has dark memories of the death of his first love. He keeps peace between the Americans and the natives who had temporarily adopted and taken care of him. The evil actions of a white sorcerer lead him to confront the villain in the Sacred Mountains, and, through shamanic rituals conquer his fears and uncover a suppressed memory he would much rather deny.