When an unknown toxic gas strikes Seoul in an unprecedented act of terror, Yong-nam has just met Eui-ju from college by chance at his mother’s birthday banquet. The city falls under sudden noxious gas attack and together, they must escape the panic-stricken city.

Oh Mal-Soon (Nah Moon-hee) is a 74-year-old widow that realizes she is becoming a burden on her family. As she is roaming the streets, she comes across a photo studio and decides to dress up for a self- portrait. When she walks out of the photo studio, she mysteriously turns back into her twenty year old self. Making the most out of this one in a lifetime opportunity, she changes her name to Oh Doo-Ri (Sim Eun-kyeong) and decides to make the most out of her youth.

Sang-hyun (Song Kang-ho), a respected priest, volunteers for an experimental procedure that may lead to a cure for a deadly virus. He gets infected and dies, but a blood transfusion of unknown origin brings him back to life as a vampire. Now, Sang-hyun is torn between faith and bloodlust, and has a newfound desire for Tae-ju (Kim Ok-vin), the wife of his childhood friend.

Dae-ho, an investigative journalist, seeks to track down the whereabouts of his son who was abducted three years ago. With the help of a detective and a psychiatrist friend, he will retrace his memory of the incident through the use of lucid dreaming techniques.