As Halloweentown prepares to celebrate its 1,000th anniversary, Marnie Piper and her brother Dylan return to Witch University, where trouble is in session from the Sinister Sisters and from someone who’s plotting to use Marnie’s powers for evil.

Marnie Piper prepares to begin a new school year, she asks the Halloweentown Hot Witches’ Council to work toward openness between Halloweentown and the mortal world. She proposes to bring a group of Halloweentown students to her own high school in the mortal world.

The Cromwell clan live in the real world, except for their grandmother who lives in Halloweentown, a place where monsters go to escape reality. But now the son of the Cromwells’ old enemy Kalabar has a plan to use the grandmother’s book to turn Halloweentown into a grey dreary version of the real world, while transform the denizens of the real world into monsters.

On her 13th birthday, Marnie learns she’s a witch, discovers a secret portal, and is transported to Halloweentown — a magical place where ghosts and ghouls, witches and werewolves live apart from the human world. But she soon finds herself battling wicked warlocks, evil curses, and endless surprises.

Kyle Fisher has one last night to celebrate life as a single man before marrying Laura, so he sets out to Vegas with four of his best buddies. But a drug and alcohol filled night on the town with a stripper who goes all the way, turns into a cold night in the desert with shovels when the stripper goes all the way into a body bag after dying in their bathroom. And that’s just the first of the bodies to pile up before Kyle can walk down the aisle…

Sexy but unstable wife and mother Jude walked out on her family three years ago. Now, just as suddenly, she is back. But her husband, Robert, has fallen in love with Callie, an assistant principal at his sons’ school. He asks Jude for a divorce. She responds by trying to turn her three boys against Callie, then by slashing herself and blaming her rival and finally by drawing her 12-year-old, Kes, into a murderous plot.