In a soon to be demolished block of apartments, the residents resist the criminal methods used to force them to leave so a greedy tycoon can build his new skyscraper. When tiny mechanical aliens land for a recharge, they decide to stay and help out.

Roberta is a bored suburban housewife who is fascinated with a woman, Susan, she only knows about by reading messages to and from her in the personals section of the newspaper. This fascination reaches a peak when an ad with the headline “Desperately Seeking Susan” proposes a rendezvous. Roberta goes too, and in a series of events involving amnesia and mistaken identity, steps into Susan’s life.