Ex-gang member John Henry is a quiet man with a violent past. When two immigrant kids on the run from his former South Los Angeles gang leader stumble into his life, John is forced to reconcile with his past in order to try and give them a future.

Seventeen-year-old Stella spends most of her time in the hospital as a cystic fibrosis patient. Her life is full of routines, boundaries and self-control — all of which get put to the test when she meets Will, an impossibly charming teen who has the same illness.

One day while returning home to stay with his widowed twin sister and her daughter, Kevin Finn, a self-centered man whose life brings him more trouble than he bargained for, is recruited by a celestial being named Yvette, who enlists Kevin with a new purpose in his life, which is to save the world.

Vice Principals tells the story of a high school and the people who almost run it, the vice principals.