On a drunk night, Shammi suggests that he and Kedar leave for America on a cruise, even though they laugh it off in that instance, in a freak accident by the sea, Kedar and Shammi who are supposed to manage a wedding baraat on a cruise, leave without the baraatis only to lose their direction and land up in Karachi, Pakistan.

Disillusioned dentist Ali Nawaab hopes to become a stand-up comedian but his attempts to find a voice on stage are hampered by memories of his blonde American muse, Ellie Goldsmith. Driven mad to the point of distraction by love, Ali must confront and exorcise the ghosts of his past in order to make his mark.