Eight people embark on an expedition into the Congo, a mysterious expanse of unexplored Africa where human greed and the laws of nature have gone berserk. When the thrill-seekers — some with ulterior motives — stumble across a race of killer apes.

FBI trainee, Clarice Starling ventures into a maximum-security asylum to pick the diseased brain of Hannibal Lecter, a psychiatrist turned homicidal cannibal. Starling needs clues to help her capture a serial killer. but her Faustian relationship with Lecter soon leads to his escape, and now two deranged killers are on the loose.