Set against the back drop of Rome in crisis, General Marcus Vinicius returns to the city from the battle fields and falls in love with a Christian woman, Lygia. Caught in the grip of insanity, Nero’s atrocities become more extreme and he burns Rome, laying the blame on the Christians. Vinicius races to save Lygia from the wrath of Nero as the empire of Rome collapses around them.

A pair of psychotic hoodlums and an equally demented nymphomaniac woman terrorize two young girls on a train trip from Germany to Italy.

In 1500, Duke Cesare Borgia hopes to marry his sister (widowed by poison) to the heir apparent of Ferrara, which impedes his conquest of central Italy. On this delicate mission he sends Andrea Orsini, his sister’s lover and nearly as unscrupulous as himself. En route, Orsini meets Camilla Verano, wife of the count of Citta’ del Monte (Borgia’s next intended conquest); and sentiment threatens to turn him against his deadly master, whom no one betrays twice…