After surviving a stabbing by a student, teacher Trevor Garfield moves from New York to Los Angeles. There, he resumes teaching as a substitute teacher. The education system, where violent bullies control the classrooms and the administration is afraid of lawsuits, slowly drives Garfield mad.

Carol, a typical upper middle-class housewife, begins to complain of vague symptoms of illness. She “doesn’t feel right,” has unexplained headaches, congestion, a dry cough, nosebleeds, vomiting, and trouble breathing. Her family doctor treats her concerns dismissively and suggests a psychiatrist. Eventually, an allergist tells her that she has Environmental Illness.