Being just a normal student without a special talent, Makoto Naegi wins a lottery to attend the prestigious Hope’s Peak Academy where only the top prodigies attend. However, instead of this being the beginning of a wonderful high school life, it’s a ticket to despair, because the only way to graduate from Hope’s Peak Academy is to kill one of your fellow students or be one of their victims.

Kamijo is a student in Academy City, where people use science to develop supernatural abilities. The guy’s got a lot of heart – luckily for a young nun named Index. She’s on the run from a sorcery society that covets the astonishing 103,000 volumes of magical knowledge stored in her memory. When Index stumbles into Kamijo’s life, she find a faithful friend and protector, and while Kamijo’s easily the weakest kid in Academy City, he’s got something else going for him: the Imagine Breaker, an unexplainable power stored in his right hand that negates the powers of others. With scientists and sorcerers attacking from all sides, the Imagine Breaker will definitely come in handy – but it’s Kamijo’s loyalty to Index that will be his greatest weapon in the fight to keep her safe.

Marika Katou, a third year student at Hakuho Girls’ Academy, is a legitimate space pirate with a Letter of Marque. Between her studies, leading her school’s space yacht club, working part time at Cafe Lamp, and being the captain of the space pirate ship Bentenmaru, Marika’s days are very busy. One day, Marika gets a job to rob a high-class passenger ship, and she discovers that on the passenger list is Kanata Mugen, a boy who owns a “galaxy pass”. Thus, an adventure featuring a hyperspace race between pirates and one young boy begins.

Witchblade is an anime series based on the American comic book by the same name. Instead of an adaptation of the original story, the producers decided to create an entire new setup, with all new characters. This co-production between Japanese studio Gonzo and American publisher Top Cow, who owns the rights for the Witchblade franchise, was licensed for release in the United States. The English dub premiered on the US cable network IFC in January 2008. The show aired on Tuesdays & Wednesdays at 3:30 AM ET, and the series finale aired on June 13, 2008, on IFC. The show is also available on a purchase-to-download system on Xbox Live and PlayStation Network. The first twelve episodes are also available for download via Amazon’s Unbox service. The show is also available on Netflix Instant Stream. As of June, 2011, it was available free on Hulu.

As of December 2008, in the USA and Canada there were 6 Volumes on DVD available, with Vol. 1 having been released in September 2007. There is also a full boxed set containing all 24 episodes and an extra disc with special features. A Blu-ray box set was released on November 3, 2009.

The anime was directed by Yoshimitsu Ohashi, who directed Galaxy Angel and Galaxy Angel Z, and the characters were designed by Uno Makoto, the character designer for Stellvia and Love Hina.