A group of passionate filmmakers venture deep into the mysterious underground Banning Tunnels, where they discover a lost city of cannibalistic, half-human, half-lizards.

Return to the Class of Nuke ‘Em High follows a young couple that are up against the school glee club. Unfortunately, the glee club has mutated into a gang called The Cretins. When the other students begin to undergo mutations, our couple must solve the mystery and save Tromaville High School