The eccentric and childish Pee-wee Herman embarks on a big adventure when his beloved bicycle is stolen. Armed with information from a fortune-teller and a relentless obsession with his prized possession, Pee-wee encounters a host of odd characters and bizarre situations as he treks across the country to recover his bike.

A young neurosurgeon inherits the castle of his grandfather, the famous Dr. Victor von Frankenstein. In the castle he finds a funny hunchback, a pretty lab assistant and the elderly housekeeper. Young Frankenstein believes that the work of his grandfather was delusional, but when he discovers the book where the mad doctor described his reanimation experiment, he suddenly changes his mind.

Hapless Henry Palfrey is patronised by his self-important chief clerk at work, ignored by restaurant waiters, conned by shady second-hand car salesmen, and, worst of all, endlessly wrong-footed by unspeakably rotten cad Raymond Delauney who has set his cap at April, new love of Palfrey’s life. In desperation Henry enrolls at the College of Lifemanship to learn how to best such bounders and win the girl.