Dave is a married man with two kids and a loving wife , and Mitch is a single man who is at the prime of his sexual life. One fateful night while Mitch and Dave are peeing in a fountain when lightning strikes, they switch bodies.

Ice Cube stars as Darius Stone, a thrill-seeking troublemaker whose criminal record and extreme sports obsession make him the perfect candidate to be the newest XXX agent. He must save the U.S. government from a deadly conspiracy led by five-star general and Secretary of Defense George Deckert (played by Willem Dafoe).