In the wake of the end of the world, a family of four desperately tries to survive. Their goal: escaping the city and traveling to the rural community they once called home. The constant threat of a violent death forcing them to stay as far away from civilization as possible, they take to the forest, soon to discover the danger posed by other survivors may be the least of their worries.

The West Jefferson Mall is closed down and set to be demolished. The department store was the site of a grizzly murder/suicide years before and now… it’s the perfect location for a wild Halloween party. Two floors, fifty thousand square feet, loud music, booze, sexy Halloween costumes, and one uninvited guest. It’s one hell of a night and by morning the only survivor, a woman with psychic abilities, is pitted in a cat and mouse game with the killer, running from room to room and using her powers to retrace the final steps of the other guests.

Two years into the outbreak, SICK roam the land and the remaining survivors struggle day-to-day trying to rebuild civilization. With the SICK more active at night time, three people need to seek shelter in an empty home.