This drama tells the story of a vampire, Park Ji-sang who works as a doctor in a hospital. Yoo Ri-ta is a hotshot heiress doctor, a star physician at the hospital and the niece of the board’s chairman. She’s snooty and cold, but highly capable, and accustomed to being the golden girl. Lee Jae-wook is their chief, an outwardly gentle, inwardly ambitious man who will prove to be their biggest adversary.

Jeonokseo, the most horrifying prison in Joseon, is where Ok Nyeo was born. This genius girl learns the art of living from the most eccentric people of the time. Despite the difficulties, Ok Nyeo grows up to introduce a human rights institution of Joseon to protect the weak.