As Po looks for his lost action figures, the story of how the panda inadvertently helped create the Furious Five is told.

After being diagnosed with Dementia, an elderly war veteran is forced by his estranged family to hire a live-in nurse, only to find she harbors a sinister secret.

Picking up directly where the previous film left off, the story follows Riley, one of the last people to come in contact with Samantha, as he scrambles to track down those responsible for the outbreak before the highly contagious disease not only consumes his body, but the world as we know it.

Michael is committed to getting his best friend Chris to sober up and get his life back on track. With the best of intentions, Michael implements a plan to convince Chris to go to rehab before his drug addiction leads to an early death. But what begins as an attempt to save his friend’s life quickly takes an unexpected turn as the two friends confront personal demons, the consequences of past actions, and forces beyond their control.