Surgeon Simon Thorne suffers from paranoia, obsessions and hallucinations, and loses both his wife and his job. But then he meets a couple from one of his dreams where they kill him. So he has to kill them first.

Surgeon Simon Thorne suffers from paranoia, obsessions and hallucinations, and loses both his wife and his job. But then he meets a couple from one of his dreams where they kill him. So he has to kill them first.

Paris-based wine expert Steven Spurrier heads to California in search of cheap wine that he can use for a blind taste test in the French capital. Stumbling upon the Napa Valley, the stuck-up Englishman is shocked to discover a winery turning out top-notch chardonnay. Determined to make a name for himself, he sets about getting the booze back to Paris.

When a freighter is viciously attacked in the Pacific Ocean, a team of experts — including biologist Niko Tatopoulos and scientists Elsie Chapman and Mendel Craven — concludes that an oversized reptile is the culprit. Before long, the giant lizard is loose in Manhattan, destroying everything within its reach. The team chases the monster to Madison Square Garden, where a brutal battle ensues.