A nomadic 16th century warrior, condemned to hell for his brutal past, seeks redemption by renouncing violence, but finds some things are worth burning for as he fights to free a young Puritan woman from the grip of evil.

A team of space marines known as the Rapid Response Tactical Squad, led by Sarge, is sent to a science facility on Mars after somebody reports a security breach. There, they learn that the alert came after a test subject, a mass murderer purposefully injected with alien DNA, broke free and began killing people. Dr. Grimm, who is related to team member Reaper, informs them all that the chromosome can mutate humans into monsters — and is highly infectious.

In the early 1800’s, a group of fur trappers and Indian traders are returning with their goods to civilization and are making a desperate attempt to beat the oncoming winter. When guide Zachary Bass is injured in a bear attack, they decide he’s a goner and leave him behind to die. When he recovers instead, he swears revenge on them and tracks them and their paranoiac expedition leader down.

England is torn in civil strife as the Royalists battle the Parliamentary Party for control. This conflict distracts people from rational thought and allows unscrupulous men to gain local power by exploiting village superstitions. One of these men is Matthew Hopkins, who tours the land offering his services as a persecutor of witches.

Stanley is infatuated with Margaret, the statuesque waitress who works with him. He meets George Spiggott AKA the devil and sells his soul for 7 wishes, which Stanley uses to try and make Margaret his own first as an intellectual, then as a rock star, then as a wealthy industrialist. As each fails, he becomes more aware of how empty his life had been and how much more he has to live for.