Lek, a Thai boxing instructor teaches Thai boxing to a group of kids for their self-defence. He is like both teacher and father to the kids – Wuth, Catt, Pong and Jib. The four have to look after Wuth’s little brother, Woon who has a heart problem. Soon, they came across a twist of fate that leads them to fight a gang of hooligans. This causes a sudden heart attack to Woon, resulting him to have a heart transplant immediately. Unfortunately, the hospital they were in has been seized by an international terrorist group led by Paeda. Unavoidably, they get involved and fight against the terrorists, as they need to save Woon’s life and help their country at the same time.

Fight everyone and trust no one: it’s the code of survival practiced by martial-arts master Casey Bowman after his life of domestic bliss is shattered by a savage act of violence. Vowing revenge, the fearless American stealthily tracks the killer from Osaka to Bangkok to Rangoon with the help of a wise and crafty sensei. His only clues: a series of victims whose necks bear the distinctive mark of strangulation by barbed wire. Fighting to avenge as well as to survive, Casey must sharpen his razor-like responses and take his battle skills to the next level, even using deep meditation to fake his own death. His target: the sinister drug lord Goro, who is flooding the streets with deadly meth cooked at his remote jungle factory. To prepare for his ultimate confrontation, Casey must finally become an invisible warrior worthy of the name Ninja. But just when his prey is cornered, an unexpected twist shows Casey that his battle is only beginning: he truly can trust no one.

In the back streets of a tourist town in present-day Southeast Asia, we find a filthy cinder block room; a bed with soiled sheets; a little girl waits for the next man. Alex (Dermot Mulroney), a human trafficking investigator, plays the role of her next customer as he negotiates with the pimp for the use of the child. Claire (Mira Sorvino), Alex’s wife, is caught up in the flow of her new life in Southeast Asia and her role as a volunteer in an aftercare shelter for rescued girls where lives of local neighborhood girl’s freedoms and dignity are threatened. Parallel story lines intertwine and unfold twists against the backdrop of the dangerous human trafficking world, in a story of struggle, life, hope and redemption in the “TRADE of INNOCENTS.”