A successful physician and devoted family man, John Dolittle (Eddie Murphy) seems to have the world by the tail, until a long suppressed talent he possessed as a child, the ability to communicate with animals is suddenly reawakened with a vengeance! Now every creature within squawking distance wants the good doctor’s advice, unleashing an outrageous chain of events that turns his world upside down!

Carol, a typical upper middle-class housewife, begins to complain of vague symptoms of illness. She “doesn’t feel right,” has unexplained headaches, congestion, a dry cough, nosebleeds, vomiting, and trouble breathing. Her family doctor treats her concerns dismissively and suggests a psychiatrist. Eventually, an allergist tells her that she has Environmental Illness.