Gerry is a talented but down-on-his-luck gambler whose fortunes begin to change when he meets Curtis, a younger, highly charismatic poker player. The two strike up an immediate friendship and Gerry quickly persuades his new friend to accompany him on a road trip to a legendary high stakes poker game in New Orleans. As they make their way down the Mississippi River, Gerry and Curtis manage to find themselves in just about every bar, racetrack, casino, and pool hall they can find, experiencing both incredible highs and dispiriting lows, but ultimately forging a deep and genuine bond that will stay with them long after their adventure is over.

Katherine Morrissey, a former Christian missionary, lost her faith after the tragic deaths of her family. Now she applies her expertise to debunking religious phenomena. When a series of biblical plagues overrun a small town, Katherine arrives to prove that a supernatural force is not behind the occurrences, but soon finds that science cannot explain what is happening. Instead, she must regain her faith to combat the evil that waits in a Louisiana swamp.