A young surgeon with Savant syndrome is recruited into the pediatric surgical unit of a prestigious hospital. The question will arise: can a person who doesn’t have the ability to relate to people actually save their lives?

A con man on the run from a vicious gangster takes cover from his past by assuming the identity of his prison cellmate, Pete, “reuniting” with Pete’s estranged family, a colorful, dysfunctional group that threatens to drag him into a world just as dangerous as the one he’s trying to escape – and, just maybe, give him a taste of the loving family he’s never had.

Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

In this mismatched buddy cop dramedy, an amazingly handsome, happy-go-lucky FBI agent is paired with a local, hard scrabble Michigan homicide detective. As they solve crimes together, their polar opposite methods only slightly outweigh their disdain for each other.