Denny has yet again been left by her thug boyfriend Chip. It seems as if she is doomed to be stuck with awful guys, this time she has to choose between nerdy Charles and the strange Kaz, who turns into a monster when sexually aroused.

Dr. Peyton Westlake is on the verge of realizing a major breakthrough in synthetic skin when his laboratory is destroyed by gangsters. Having been burned beyond recognition and forever altered by an experimental medical procedure, Westlake becomes known as Darkman, assuming alternate identities in his quest for revenge and a new life with a former love.