The year is 2048, and global warming has flooded much of Earth’s land areas. A father and his two sons try to salvage treasures from sunken buildings when they are given an important assignment by the New Vatican.

When a cockroach-spread plague threatened to decimate the child population of New York City in the original Mimic, biologist Susan Tyler and her research associates developed a species of “Judas” bugs and introduced them into the environment, where they were to “mimic” the diseased roaches and infiltrate their grubby habitats. The plan worked until the bugs evolved to mimic their next prey…..humans! Just when they were all thought to be dead, the giant cockroaches are back, and this time they’ve mutated to take on human form!