Benji is lost and becomes a stray animal in Athens, Greece, trying to reunite with his family while secret agents pursue him, trying to get a formula which was glued to his paw in order to get it past customs.

Benji has become stranded on a remote island after a boating accident. He finds himself struggling to survive in the wilderness, avoiding close encounters with a wolf, a bear, and a territorial female cougar with her cub.