After the mysterious death of scientist, Dr. Devin Villiers, Det. Frank Turner and his partner are assigned to protect Villiers’ colleague, who revealed that a veteran soldier was subjected to an experiment with the objective of creating the ultimate national security weapon… an undetectable soldier. The experiment failed – with disastrous side effects.

Desperate for companionship, the repressed Willard befriends a group of rats that inhabit his late father’s deteriorating mansion. In these furry creatures, Willard finds temporary refuge from daily abuse at the hands of his bedridden mother and his father’s old partner, Frank. Soon it becomes clear that the brood of rodents is ready and willing to exact a vicious, deadly revenge on anyone who dares to bully their sensitive new master.