New York City. Melvin Udall, a cranky, bigoted, obsessive-compulsive writer, finds his life turned upside down when neighboring gay artist Simon is hospitalized and his dog is entrusted to Melvin. In addition, Carol, the only waitress who will tolerate him, must leave work to care for her sick son, making it impossible for Melvin to eat breakfast.

A group of men who were clearing bush for the government arrive back in town, claiming that their friend was abducted by aliens. Nobody believes them, and despite a lack of motive and no evidence of foul play, their friends’ disappearance is treated as murder.

New Yorkers, Skip Donahue and Harry Monroe, have no jobs and no prospects. They decide to flee the city and find work elsewhere, and land jobs as woodpeckers to promote the opening of a bank. When their feathery costumes are stolen and used in a bank robbery, they no longer have to worry about employment — they’re sent to prison!

A young neurosurgeon inherits the castle of his grandfather, the famous Dr. Victor von Frankenstein. In the castle he finds a funny hunchback, a pretty lab assistant and the elderly housekeeper. Young Frankenstein believes that the work of his grandfather was delusional, but when he discovers the book where the mad doctor described his reanimation experiment, he suddenly changes his mind.

Intent on seeing the Cahulawassee River before it’s turned into one huge lake, outdoor fanatic Lewis Medlock takes his friends on a river-rafting trip they’ll never forget into the dangerous American back-country.