Seven years on from the events of Monsters, and the ‘Infected Zones’ have spread worldwide. Humans have been knocked off the top of the food chain, with disparate communities struggling for survival. American soldiers are being sent abroad to protect US interests from the Monsters, but the war is far from being won.

An unemployed cartoonist moves back in with his parents and younger brother Freddy. When his parents demand he leave, he begins to spread rumors that his father is sexually abusing Freddy.