After several coeds are murdered at a college, a professor (Fabio Testi) who is involved with a student becomes a suspect, along with several other male and female teachers.

A grizzled ex-sheriff helps a man framed for murder to confront the powerful trio of brothers who want him dead.

While the Civil War rages between the Union and the Confederacy, three men – a quiet loner, a ruthless hit man and a Mexican bandit – comb the American Southwest in search of a strongbox containing $200,000 in stolen gold.