Sisters Myra and Ellie have finally had enough of their miserable, dead-end lives. When their stepfather Charley (the titular “Bonnie” being long dead) tried to rape Myra, Ellie ventilates him with a shotgun, and the pair run off to their wealthy uncle’s mansion in El Paso. From that point on, the two undergo a transformation in their personalities, and start to enjoy living their lives on the wild side.

A cowboy rides into a small town that is ruled with an iron fist by a corrupt sheriff. He becomes involved with a pretty young town girl and some residents who are trying to oust the sheriff, resulting in a robbery, a murder and his being pursued by a vengeful posse.

When exposure to a combination of radiation and insecticide causes Scott Carey to begin to shrink medical science is powerless to help him.